Dextromethorphan Inhibits Activations and Functions in Dendritic Cells

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Dextromethorphan Inhibits Activations and Functions in Dendritic Cells

Dendritic cells (DCs) play an important role in connecting innate and adaptive immunity. Thus, DCs have been regarded as a major target for the development of immunomodulators. In this study, we examined the effect of dextromethorphan (DXM), a common cough suppressant with a high safety profile, on the activation and function of DCs. In the presence of DXM, the LPS-induced expression of the cos...

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ژورنال

عنوان ژورنال: Clinical and Developmental Immunology

سال: 2013

ISSN: 1740-2522,1740-2530

DOI: 10.1155/2013/125643